BUY MODd GRF GHRP-6 BLEND PEPTIDE FOR SALE ONLINE
Modified GRF 5mg, GHRP-6 5mg (10mg Total Blend)
What is the Mod GRF (1-29) & GHRP-6 peptide blend?
Mod GRF (1-29) & GHRP-6 are two synergistic peptides. These peptides appear to work together effectively to increase the release of growth hormone (GH). The full structure of Growth Hormone Releasing Hormone (GHRH) contains 44 amino acids. Researchers have noticed that the first 29 amino acids (1-29) contain the full biological activity of GHRH. This fraction is called Growth Hormone Releasing Factor (GRF 1-29).
GRF 1-29 appears to be biologically more active and has a longer duration of action as it evades metabolic clearance. Similarly, Growth Hormone Releasing Peptide-6 (GHRP-6) is under study as a potent stimulator of growth hormone release from the anterior pituitary gland. According to the researchers “These results provide evidence that the GH-stimulatory effects of GHRP-6 are achieved through activation of the PI second messenger system and thus support earlier findings that PKC and Ca2+ play central roles in mediating the effects of GHRP-6.”
Using a blend of Mod GRF (1-29) & GHRP-6 may lead to superior growth hormone release and better outcomes than using either of these peptides alone.
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Modified GRF (1-29) Specifications
MOLECULAR FORMULA: C152H252N44O42
MOLECULAR WEIGHT: 3367.95 g/mol
CAS NUMBER: 863288-34-0
PUBCHEM: CID 56841945
MOLECULAR FORMULA: C46H56N12O6
MOLECULAR WEIGHT: 873.032 g/mol
CAS NUMBER: 87616-84-0
SEQUENCE: L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysergamide, triacetate
PUBCHEM: CID 9919153
Guide to Mod GRF 1-29 & GHRP-6 Peptide Blend
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic peptide developed to stimulate the release of growth hormone from the pituitary gland by mimicking the effects of ghrelin. It is classified as ghrelin mimetic or GHS. It is composed of six amino acids and is classified as a hexapeptide. GHRP-6 has been studied for its potential, including in the mitigation of growth hormone deficiency and cachexia (muscle wasting).
Modified (Mod) GRF 1-29, also known as CJC-1295 without DAC, is a synthetic peptide developed to act as a growth hormone-releasing hormone (GHRH) analog. It comprises 29 amino acids and is a tetrasubstituted version of the GRF 1-29 (also known as Sermorelin). GRF 1-29 is the smallest fragment of the GHRH peptide sequence, which may have the same potential for stimulating growth hormone release.
As summarized below, researchers have studied the peptides independently and for different potential action. GHRP-6 is suggested to induce potential action in:
- possible increased appetite
- possible improved muscle growth
- possible weight gain
- possible enhancement of immune function and tissue repair
Mod GRF 1-29 has been primarily researched for its potential to stimulate the release of growth hormone from the pituitary gland, which can have a range of actions. These may include the following:
- possible increased muscle mass
- possible decreased body fat
- possible improved bone density
- possible increased energy levels
Research and Clinical Studies
Mod GRF 1-29 & GHRP-6 Peptide and Muscle Mass
GHRP-6 and Mod GRF 1-29 have been suggested by researchers to exert anabolic properties by increasing growth hormone levels. For example, clinical studies with GRF 1-29 suggest that it may increase nocturnal growth hormone levels, serum levels of IGF-I and IGFBP-3, and GHBP concentrations. As a result, male test subjects who were presented the peptide for four months reportedly experienced a significant increase in lean body mass by 1.26 kg. Yet, the study suggests that GHRH analog presentation may induce anabolic effects. The peptide also appeared to induce a possible increase in skin thickness in male subjects and possible improved insulin sensitivity.
Another trial supported the hypothesis that GRF (1-29) might increase GH and IGF-I levels and improve skeletal muscle function and metabolism in ambulatory, non-obese subjects aged 64 to 76 years with low baseline IGF-I. More specifically, GRF (1-29) appeared to increase mean nocturnal GH release, GH peak amplitude, and two measures of muscle strength and a muscle endurance test.
GHRP-6 also may have anabolic potential, according to studies which are likely mediated via its growth hormone and IGF-1 stimulating action. One experiment with cultured myoblast cells reported that the peptide appeared to increase the expression of myogenic marker proteins, insulin-like growth factor-1, collagen type I, and metabolic activity in the myoblasts. Thus, the scientists concluded that the peptide GHRP-6 might improve muscle condition by stimulating collagen type I synthesis and key proteins.
Mod GRF 1-29 & GHRP-6 Peptide and Growth Hormone Deficiency
GRF 1-29 and GHRP-6 have been investigated for their potential to stimulate growth in GH deficient subjects, and clinical trials suggest potential. One clinical study investigated the potential of GRF 1-29 for subjects with growth hormone deficiency. In total, 110 subjects were given the peptide once daily for up to 1 year, and the main outcomes measured were linear growth enhancement and bone age progression. The peptide appeared to exhibit a significant increase in height velocity, with 74% of the subjects having a reportedly enhanced response after six months. The bone age to height age ratio was reported to remain stable. The researchers concluded, “No change in fasting glucose concentration or excessive generation of insulin-like growth factor I occurred, and overall GHRH was well tolerated.”
Another clinical trial aimed to investigate the potential of GHRP-6 in stimulating growth hormone (GH) secretion in subjects with normal height. The study included 13 subjects, and the results suggested that the GH response to GHRP-6 was reportedly significant and comparable to that of other GHSs.
Mod GRF 1-29 & GHRP-6 Peptide and Wasting, Cachexia
Mod GRF 1-29 and GHRP-6 may have the potential to increase growth hormone and IGF-1 levels, which may have anti-catabolic actions on muscle tissue. For example, GRF 1-29 was suggested to significantly increase growth hormone peak levels in subjects, even though the potential was slightly attenuated in those with growth hormone deficiency. Despite no direct research on Mod GRF 1-29 (without DAC), studies on Mod GRF 1-29 with DAC report apparently increased HGH and IGF-1 levels in the test subjects.
GHRP-6 may also cause a dramatic increase in growth hormone levels in subjects, according to researchers in clinical trials. For example, Cordido et al. suggested that GHRP-6 might increase GH secretion in 19 obese subjects. The scientists noted that GHRP-6 appeared more impactful than GHRH alone, stating, “GH responses to GHRP-6 were almost twice those to GHRH in obese patients.” GHRP-6 was developed with the intention of having potential as a ghrelin mimetic. Studies suggest that mimetics have shown promise in reversing protein breakdown and weight loss in catabolic states. Ghrelin has various potential actions on regulating appetite, body composition, growth hormone secretion, and energy expenditure. It may also have anti-inflammatory, anti-apoptotic, and anxiolytic potential as well.
Mod GRF 1-29 & GHRP-6 peptide is available for research and laboratory purposes only. Please review and adhere to our Terms and Conditions before ordering.
Research on Mod GRF (1-29) & GHRP-6
MOD GRF (1-29) & GHRP-6 PEPTIDES AND BRAIN HEALTH
Mod GRF (1-29) and GHRP-6 has the potential to help improve mental health and improve neurodegenerative conditions. This could be particularly useful in conditions such as Alzheimer’s and Parkinson’s disease. The peptide blend is also being studied for its potential to affect overall mental well-being and vitality, and for its viability to be used in conditions such as depressive disorders. GHRP-6 may also help with memory improvement and better learning. Studies in rodents reported that using GHRP-6 appeared to help retain more memories and aid in turning short-term memories into long-term memories. Research also suggests that GH analogs, such as GHRP-6, can assist spatial learning. GHRP-6 could be useful in situations such as acute stroke, as it may provide improved functional aspects of brain function, such as spatial learning, problem-solving, and creating thinking. Research suggests that using GHRP-6 and other ghrelin analogs may improve the supply of blood to the brain. This would prevent the development of new strokes and improve recovery following established strokes by reducing infarct size and promoting new tissue development. Mod GRF (1-29) & GHRP-6 blend could help reduce apoptosis in brain cells, lower inflammation, and prevent age-related structural and functional decline in brain function.
MOD GRF (1-29) & GHRP-6 PEPTIDES AND ANTI-AGING
The levels of growth hormone peak during the early teenage years and decline after that. The aging process is a direct consequence of declining levels of growth hormone. Many anti-aging treatments and processes aim to naturally increase the levels of growth hormones in the body. The synergy of Mod GRF (1-29) and GHRP-6 appear to naturally increase growth hormone levels and thereby reverse the aging processes. This reversal is mostly due to the potential ability of these peptides to boost cellular repair, reduce cellular damage due to oxidative stress, and reduce telomere shortening.
MOD GRF (1-29) & GHRP-6 PEPTIDES AND WOUND HEALING
Mod GRF (1-29) & GHRP-6 in combination appears to increase tissue synthesis and promote wound healing. GHRP-6 interacts with CD36 receptors known to promote angiogenesis, which is the growth of new blood vessels. The researchers report that “In covalent competition binding studies with the GHRP-6 prototype hexarelin bearing a radiotracer, certain [aza-Glu]GHRP-6 azapeptides retained relatively high (2-27 μM) affinity for the CD36 scavenger receptor.” The growth of new blood vessels in wounds improves wound healing. Animal studies have observed that GHRP-6 appears to improve wound closure, increasing the synthesis of extracellular proteins like collagen, and stimulating scar formation. This potential ability of this peptide blend may eventually be used in clinical practice to achieve superior aesthetic outcomes in cosmetic surgeries.
MOD GRF (1-29) & GHRP-6 PEPTIDES AND HEART DISEASE
Oxidative stress results in increased Reactive Oxygen Species (ROS) that damage the heart tissues and can result in heart damage. Research suggests that GH analogs such as Mod GRF (1-29) and GHRP-6 may reduce the levels of oxidative stress, lower the risk of heart attacks, and protect vulnerable but still viable cells. These peptides may also improve cardiovascular health by promoting a healthy lipid profile, including increased triglyceride breakdown.
MOD GRF (1-29) & GHRP-6 PEPTIDES AND MUSCLE GROWTH
Muscle growth is one of the most studied effects of growth hormones. Growth hormone analogs such as Mod GRF (1-29) & GHRP-6 have been studied for their potential to increase muscle mass via two different mechanisms: muscle hypertrophy and hyperplasia. Muscle hypertrophy results in increased muscle mass due to the increased size of already present muscle fibers. Muscle hyperplasia increases muscle mass by increasing the number of muscle fibers.
MOD GRF (1-29) & GHRP-6 PEPTIDES AND BONE DEVELOPMENT
Growth hormone analogs appear to mediate many of their effects on bone mass via Insulin-Like Growth Factor 1 (IGF-1). IGF-1 promotes the growth, differentiation, and survival of bone-forming cells. IGF-1 improves the mineralization of bones and increases bone mineral density. In addition, it also prevents the excessive hormone-induced loss of bones. This way, GH/IGF-1 interplay improves bone quality and reduces the risk of conditions such as osteoporosis.
To conclude, the Mod GRF (1-29) & GHRP-6 peptide blend may have various clinical and biological effects. This blend appears to increase the levels of the GH/IGF-1 axis. It has been observed to exhibit cellular proliferating and cytoprotective activities. This blend been studied for its potential protective effects against cellular damage resulting from increasing inflammation and oxidative stress. Moreover, this blend may increase cellular proliferation and improve healthy tissue healing.
Buy Wholesale Mod GRF GHRP-6 Blend From USA Peptide Store
At USA Peptide Store, our research peptides are of the highest purity and pharmaceutical grade. Our Mod GRF GHRP-6 Blend Peptide comes in 10mg blend (Modified GRF 5mg, GHRP-6 5mg). We’re passionate about our products, and we always strive to provide our customers with the best in both selection and quality. All of the products we provide are tested to verify authenticity and purity, so you can conduct your research with confidence.
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