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hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
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hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
hGH Fragment 176-191 Peptide For Sale
Home HGH Peptides hGH Fragment 176-191 5mg & 10mg
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hGH Fragment 176-191 5mg & 10mg

$46.00 – $65.00

HGH Fragment 176-191 is a small, synthetic piece of natural human growth hormone (hGH). It is often referred to as the “lipolytic fragment” for its ability to boost fat loss. It has been shown to help lowers blood sugar levels and promote cartilage healing without increasing long bone growth, increasing IGF-1 levels, or altering insulin sensitivity.

Fragment 176-191 is a research peptide and for study only. It is one of the strongest human growth hormones available. Research so far has discovered it to be very effective in weight loss and sustaining the fat loss.

Fragment 176-191 is a man-made growth hormone peptide and has the capability to reduce fat.  This is a research peptide and still being investigated. From studies so far its copies the body’s natural growth hormone and controls fat metabolism. It has no effect on growth resistance or insulin resistance. A possible treatment for obesity.

 

PRODUCT USAGE WARNING : This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.

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BUY HGH FRAGMENT 176-191 PEPTIDE FOR SALE ONLINE

What Is Fragment 176-191?

Fragment 176-191 (modified version of AOD9604) is a small piece of human growth hormone (hGH) that is sometimes referred to as the “lipolytic fragment.” Fragment 176-191 earned this latter name due to the fact that laboratory research has shown it to enhance fat burning, particularly in mice genetically engineered to produce large fat stores. Fragment 176-191 has been heavily researched in animal models because even while it preserves the fat-burning effects of hGH, it avoids some other effects of its parent protein such as increasing insulin-like growth factor-1 (IGF-1) levels, negatively impacting carbohydrate metabolism, altering insulin sensitivity, increasing long bone growth, and so forth. The targeted effects of fragment 176-191 make it useful for exploring human fat metabolism and may eventually provide the basis for developing anti-obesity medications.

hGH Fragment 176-191 Peptide For Sale online only at USA Peptide Store where you can buy USA Research Peptides online. Shop over 100 research peptides online now for fast shipping and the best deal! Buy in bulk and Save! USA Peptide Store Your #1 Trusted USA Research Peptides Supplier.

If this product does not meet your needs or interests, you may want to look at Ipamorelin Peptide 2mg & 5mg and Humanin Peptide 10mg. Please visit this link for further information on our HGH Peptides and Other Peptides


Fragment 176-191 Peptide Structure

Fragment 176-191 Peptide Structure

Source: PubChem

Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Molecular Formula: C78H125N23O23S2
Molecular Weight: 1817.12 g/mol
CAS Number: 66004-57-7


Fragment 176-191 Effects

1. Lowers Blood Sugar

Research in animals has revealed that the c-terminal end of hGH is primarily responsible for the protein’s hypoglycemic (lowering blood sugar) effects. Testing of at least six different fragments derived from this section of hGH has shown that fragment 176-191 is the most effective synthetic derivative of hGH for lowering blood sugar levels. This effect is secondary to a sustained increase in plasma insulin levels. There is some interest in using fragment 176-191 as a treatment for both prediabetes and type 2 diabetes.

2. Fat Burning And Weight Loss

Fragment 176-191 has earned the nickname of “lipolytic fragment” because testing in mice has revealed the peptide to have substantial fat burning and weight loss properties. It is thought that this action is mediated through an increase in production of beta-3 adrenergic receptors (β3-AR or ADRB3). Agonist action at ADRB3 is known to directly increase fat burning in adipose tissue and is also responsible for thermogenesis in skeletal muscle. Mice that have been genetically modified to produce no ADRB3 do not respond to the lipolytic effects of hGH or fragment 176-191.

Studies show that the increased fat burning associated with fragment 176-191 directly correlates with energy expenditure and thus weight reduction, leading to a nearly 50% reduction in weight gain in obese animals over a three-week course. Interestingly, the weight loss effects were seen only in obese mice, with lean mice maintaining normal body weight, on average, even when exposed to fragment 176-191. These findings indicate that there are secondary regulatory pathways for lipolysis that override ADRB3 function when body weight is at or near ideal, opening up areas for additional research into energy homeostasis.

Body weight in genetically obese mice after two weeks of treatment with a single daily dose of fragment 176-191

Body weight in genetically obese mice after two weeks of treatment with a single daily dose of fragment 176-191
Source: Oxford Academic

Effect of saline (control), fragment 176-191, and hGH on white adipose tissue mass in obese mice over 14 days

Effect of saline (control), fragment 176-191, and hGH on white adipose tissue mass in obese mice over 14 days
Source: Oxford Academic

3. Promotes Cartilage Regeneration

Though fragment 176-191 is primarily of interest for its lipolytic properties, the peptide is under investigation for other possible benefits. Of note, a 2015 article out of Korea revealed that fragment 176-191 may be able to potentiate the effects of hyaluronic acid injections in promoting cartilage regeneration. Studies in rabbits indicated that weekly injections of fragment 176-191 increase laboratory measures of cartilage growth and that co-administration of the peptide with hyaluronic acid (HA) produces even more substantial effects. Similarly, the study found that fragment 176-191, both alone and in combination with HA, reduces disability associated with osteoarthritis. There is hope that this may lead to advanced therapies for osteoarthritis and may even eliminate the need for surgery in certain settings.


Fragment 176-191 Safety Studies

There is some concern that the use of hGH or its derivatives for weight control may have unwanted side effects. This concern arises from the fact that studies of hGH have shown that long-term exogenous administration, while increasing lean body mass and decreasing adipose tissue, can also cause:

  • increased insulin resistance,
  • diabetes,
  • acromegaly,
  • cancer,
  • hypertension (high blood pressure), and
  • edema (swelling).

In 2013, a study published in the Journal of Endocrinology and Metabolism evaluated six studies of fragment 176-191 to assess the rate and significance of negative effects associated with the peptide. The study, included only research that followed the randomized, double-blinded, placebo-controlled model of a phase IIb clinical trial in order to keep the highest possible standards of evidence. It found that IV and oral administration of Fragment 176-191, when compared to placebo, led to no changes in:

  • physical findings,
  • laboratory parameters,
  • glucose levels,
  • glucose tolerance,
  • insulin sensitivity,
  • IGF-1 levels, or
  • rates of adverse events (e.g. headache).

The results of this meta-analysis suggest that fragment 176-191 offers many of the benefits of hGH without the associated negative (and often serious) side effects. These findings further the argument for pursuing regulatory approval for use of fragment 176-191 in the clinical setting, but also offer insight into the regulation of human growth, fat deposition, and energy homeostasis. These findings make it clear that it is possible to target fat loss without affecting energy homeostasis in other nutrient pathways, opening the door for a deeper exploration of human energy regulation and methods of manipulating it.

It is worth noting that while hGH has anabolic effects on muscle, fragment 176-191 was specifically selected for its ability to avoid anabolism entirely. This is critical to ensuring that the peptide has targeted lipolytic effects and does not produce acromegaly or any of the other conditions associated with hGH administration. Studies in mice reveal that fragment 176-191 does not increase cell proliferation.


Fragment 176-191 Future Research

The primary area of research for fragment 176-191 is in weight loss and lipolysis where significant effort is being expended to learn how the peptide can be used to understand fat metabolism and energy homeostasis. The most active secondary area of research is in connective tissue regeneration, particularly cartilage repair.

Buy Wholesale hGH Fragment 176-191 Peptide From USA Peptide Store

At USA Peptide Store, our research peptides are of the highest purity and pharmaceutical grade. Our hGH Fragment 176-191 Peptide comes in 5mg and 10mg. We’re passionate about our products, and we always strive to provide our customers with the best in both selection and quality. All of the products we provide are tested to verify authenticity and purity, so you can conduct your research with confidence.

Searching for hGH Fragment 176-191 Peptide for sale? Look no further! Our online peptide store offers a wide range of hGH Fragment 176-191 Peptide, perfect for your research needs. Whether you’re in the United States, Australia, Canada, Germany, Sweden, France, Turkey, Thailand, Italy, Netherlands or the United Kingdom, we have you covered. We provide fast and secure shipping to multiple countries, ensuring that you receive your order conveniently and on time. Purchase hGH Fragment 176-191 Peptide that are now available for sale and in stock. With our competitive prices and extensive inventory, you can trust us to be your reliable source for hGH Fragment 176-191 5mg & 10mg.

Want to learn more about our products or have a question about payment options? Our customer service team is here to help.  So, what are you waiting for? order hGH Fragment 176-191 Peptide For Sale and experience first-hand quality service, prompt response and quick shipping. Stock up on the highest quality hGH Fragment 176-191 Peptide For Sale and more at USA Peptide Store today.

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