Tripeptide-29 Peptide (Collagen Peptide)

Welcome to the definitive information hub for Tripeptide-29 (CAS: 2239-67-0) here at Buy Peptides Online USA. As a leading supplier dedicated to the scientific community, we understand that quality and purity are non-negotiable. We don't just sell peptides; we provide the assurance and analytical rigor required for serious investigation.

If you are looking to buy Tripeptide-29 Peptide online in the USA, you have found your trusted source. Below you will find a comprehensive breakdown of this powerful collagen peptide, its structural characteristics, verified specifications, and the premium support systems we provide with every order.

🔬 What is Tripeptide-29? (Gly-Pro-Hyp)

Tripeptide-29, scientifically known as H-Gly-Pro-Hyp-OH, is a synthetic, ultra-small biomimetic peptide that replicates the specific amino acid sequence—Glycine, Proline, and Hydroxyproline—found abundantly in Type I collagen . Unlike larger, full-length collagen proteins, this tripeptide fragment represents the minimal functional unit required to signal skin fibroblasts. Because its molecular weight is exceptionally low, it offers superior permeability and bioavailability in research models compared to traditional collagen hydrolysates .

Often referred to as the "Collagen Peptide" or "Collagen Tripeptide," it is not a growth factor or a hormone. It is a signaling molecule that tells aging cells to behave like young cells again.

🧪 Peptide Structure & Verification

Understanding the chemical architecture of your research compounds is vital. We provide full transparency regarding the identity of our Tripeptide-29.

Molecular Integrity:

• Sequence: Gly-Pro-Hyp (GPX)
• Molecular Formula: C12H19N3O5
• Molecular Weight: 285.30 g/mol
• CAS Number: 2239-67-0

Quality Verification (COA & HPLC/MS):
At Buy Peptides Online USA, every vial of Tripeptide-29 is accompanied by a Certificate of Analysis (COA) . We utilize rigorous High Performance Liquid Chromatography (HPLC) to quantify purity and Mass Spectrometry (MS) to confirm the exact molecular weight and structural sequence . Our current research batch verifies a purity rating of >99% , ensuring that your variables are controlled and your data is reproducible.

📊 Technical Specifications & Data Sheet

To assist researchers in protocol preparation, we have compiled the verified specifications below:

💡 Primary Research Applications & Mechanism of Action

Tripeptide-29 is rapidly gaining traction in dermatological and metabolic research due to its dual-action modality. Our clients frequently investigate this peptide for the following high-value research focuses:

1. 🧬 Recovery, Healing & Collagen Support (Anti-Photoaging)

The primary function of Tripeptide-29 is the restoration of the Extracellular Matrix (ECM). It acts by attenuating the expression of Matrix Metalloproteinases (MMP-1 and MMP-3)—the enzymes responsible for breaking down collagen . Concurrently, it activates TGF-β signaling, effectively "switching on" the fibroblast's machinery to produce fresh, structural Type I and Type III collagen . This makes it a critical compound for research involving dermal density, wound healing models, and UV-induced damage repair.

2. 🧠 Metabolic & Glucose Homeostasis Research

Emerging studies suggest that Gly-Pro-Hyp acts as a competitive inhibitor of Dipeptidyl Peptidase-IV (DPP-IV) . By inhibiting DPP-IV, this peptide may help prolong the half-life of incretins such as GLP-1. Researchers are currently investigating its potential role in weight management and glycemic control models, independent of caloric restriction .

3. 🛡️ Anti-Inflammatory & Antioxidant Defense

Tripeptide-29 has demonstrated significant potential in reducing oxidative stress markers. It helps interrupt chain oxidation reactions and reduces the accumulation of Advanced Glycation End products (AGEs), which are primary contributors to cellular senescence .

❓ Frequently Asked Questions (FAQ)

Q: How do I reconstitute and store Tripeptide-29?

A: As a lyophilized powder, Tripeptide-29 is hygroscopic. We recommend centrifuging the vial briefly to ensure the powder collects at the bottom. Reconstitute with sterile water, PBS, or bacteriostatic water. Once reconstituted, aliquot the solution to avoid repeated freeze-thaw cycles and store at -20°C to -80°C for optimal stability .

Q: What is the difference between Tripeptide-29 and standard Collagen?

A: Standard collagen is a large, full-length protein with a high molecular weight, making topical penetration or rapid bioavailability difficult. Tripeptide-29 is the pre-digested, bioactive fragment. It is the specific sequence responsible for sending regenerative signals to the cell, making it far more efficient in controlled research settings .

Q: Is the Certificate of Analysis (COA) available?

A: Yes. Every purchase includes access to the batch-specific COA. This document verifies the results of our HPLC purity analysis and MS structural confirmation.

Q: Is this product suitable for cosmetic formulation?

A: While Tripeptide-29 is a popular INCI ingredient in cosmetics , the product sold on this page is strictly for laboratory research and development purposes. It is sold as a raw material for scientific investigation and is not intended for direct retail formulation or personal care use unless you are a licensed manufacturer performing stability testing.

✨ Why Choose Buy Peptides Online USA? (Value Propositions)

When you decide to buy Tripeptide-29 online, you are entrusting your research to a partner. Here is why discerning scientists choose us:

✅ Authenticity Guarantee: We source exclusively from GMP-compliant facilities . Every batch is verified via Third-Party HPLC/MS testing in the USA.
✅ Premium Packaging: Peptides are shipped in sealed, moisture-proof vials with desiccant packs to maintain integrity during transit. We ship with ice packs to preserve activity .
✅ Rapid Domestic Shipping: We are based in the USA. No international customs delays. Expect your research materials within 2-3 business days.
✅ Technical Consultation: Our support team is trained to understand peptide handling. We are here to assist with solubility issues or storage protocols.

📦 Handling, Storage & Laboratory Use

Handling:

• Use sterile, low-binding pipette tips when handling reconstituted peptides.
• Always wear appropriate PPE (gloves, lab coat) when handling lyophilized powders.

Storage:

• Lyophilized Powder: Store at 2°C to 8°C (refrigerated). Do not expose to direct sunlight or excessive humidity.
• In Solution: Store at -20°C. Avoid freeze-thaw cycles. Discard any unused solution after 30 days post-reconstitution .

Warning:
This product is sold for Laboratory Research Use Only. It is not a drug, food, or cosmetic. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. By purchasing from Buy Peptides Online USA, you certify that you are a qualified researcher or a commercial entity utilizing this product for chemical analysis and in-vitro testing only.

🚚 Shipping, Payment & Services

We strive to make the procurement process as seamless as your research.

• Payment: We accept all major credit cards, PayPal, and Cryptocurrency. High-risk transactions are processed securely via verified merchant gateways.
• Shipping: Flat rate shipping available. Free shipping on orders over $200. Tracking numbers provided instantly upon label creation .
• 24/7 Support: Have a question about your order at 10 PM? Our ticketing system is monitored around the clock.
• Product Replacement: In the unlikely event of damage during transit (e.g., vial broken, thawed with warm packs), we offer a hassle-free replacement policy.

Ready to elevate your research?
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