Mod GRF, GHRP-2 (Blend)

Welcome to the definitive research guide for the Mod GRF, GHRP-2 (Blend) , available exclusively from Buy Peptides Online USA. As a trusted source to buy research peptides online in the USA, we ensure every product meets the highest standards of quality and documentation for laboratory use. This blend represents a sophisticated tool for investigators focusing on the synergistic stimulation of the Growth Hormone (GH) axis, combining a stable Growth Hormone Releasing Hormone (GHRH) analog with a potent Growth Hormone Secretagogue (GHRP).

What Is the Mod GRF (1-29) and GHRP-2 Blend?

This product is a pre-formulated, synergistic peptide blend designed for advanced endocrine research. It combines two distinct peptides in a single vial to facilitate the study of the Growth Hormone (GH) axis through complementary pathways .

• Mod GRF (1-29) – Modified GRF (CJC-1295 without DAC): This is a synthetic analog of Growth Hormone Releasing Hormone (GHRH), specifically the bioactive 1-29 amino acid fragment. The term “Mod GRF” refers to modifications (often including substitutions like replacing the second amino acid with D-Ala) that make the peptide highly resistant to enzymatic degradation by dipeptidyl aminopeptidase IV . The “No DAC” (Drug Affinity Complex) formulation ensures a short half-life, mimicking the body’s natural pulsatile release of GHRH. It functions by binding to GHRH receptors on pituitary somatotroph cells, activating adenylate cyclase and elevating intracellular cyclic AMP (cAMP) levels .
• GHRP-2 (Growth Hormone Releasing Peptide-2): Also known as Pralmorelin, this is a synthetic hexapeptide belonging to the GHRP class. It acts as an agonist of the ghrelin receptor (GHSR-1a), initiating intracellular signaling cascades distinct from GHRH. This includes activating phospholipase C, generating inositol triphosphate, and mobilizing intracellular calcium . GHRP-2 also functions by inhibiting somatostatin, the natural “brake” on GH release .

When combined, this blend allows researchers to investigate the dual-pathway stimulation of GH secretion: Mod GRF stimulates the pituitary via the GHRH receptor/cAMP pathway, while GHRP-2 stimulates GH release via the GHSR pathway and inhibits somatostatin. This synergistic mechanism is a primary focus of modern endocrine research, producing a more robust GH pulse than either peptide alone .

Peptide Structure & Specifications

For rigorous scientific inquiry, understanding the molecular foundation of your research compounds is non-negotiable. Below are the verified specifications for the components of this blend .

Technical Specifications & Molecular Data

Primary Research Applications

This blend is a staple in laboratories focused on endocrinology, metabolism, regenerative science, and neurobiology. The synergistic nature of these two compounds opens several avenues for investigation. When you choose to buy Mod GRF GHRP-2 online, researchers typically focus on the following areas :

• 🔬 Growth Hormone Signaling Research: The primary function of this blend is to model and study the pulsatile release of Growth Hormone (GH) and the subsequent hepatic production of Insulin-like Growth Factor 1 (IGF-1). It serves as a precise tool for analyzing pituitary signaling, receptor synergy, and endocrine regulation mechanisms .
• ⚙️ Metabolic & Body Composition Studies: Researchers utilize this blend to investigate mechanisms of lipid metabolism (lipolysis) and protein synthesis in cellular and animal models. It provides data on how metabolic pathways, including glucose homeostasis and insulin sensitivity, are regulated by the GH/IGF-1 axis .
• 🩻 Regenerative & Musculoskeletal Research: Pre-clinical studies explore the role of amplified GH signaling in tissue repair, cellular regeneration, and recovery models, particularly concerning muscle tissue and bone density. The peptides are used to study osteoblast activity, calcium retention, and muscle cell repair following injury or atrophy .
• 🔬 Insights into Cellular Aging: Cellular aging research represents another intriguing domain. By utilizing these peptides, researchers might explore how modulating growth hormone pathways might influence markers of cellular aging, senescence, and autophagy in experimental models .
• 🧠 Neurobiological Research: Emerging data suggests that GH pathways may play a role in neurobiology. The blend might serve as a model for investigating the impact of GH on neurogenesis, cognitive function, and neuroprotection, particularly in brain regions associated with learning and memory like the hippocampus .

Quality Assurance: HPLC, Mass Spec, and COA

At Buy Peptides Online USA, the integrity of your research is our priority. We ensure that every batch of our Mod GRF & GHRP-2 Blend is subjected to rigorous analytical testing. This commitment is why informed researchers choose to buy peptides USA from us.

• 🧪 Certificate of Analysis (COA): Each product is accompanied by a batch-specific COA. This document provides a detailed breakdown of the testing results, confirming the identity, purity, and concentration of the peptide.
• ⚗️ High-Performance Liquid Chromatography (HPLC): HPLC is the gold standard for determining purity. Our peptides undergo HPLC analysis to verify that the purity meets or exceeds ≥99% , ensuring that the results in your lab are not confounded by unknown impurities .
• 🔬 Mass Spectrometry (MS): MS analysis is used to confirm the exact molecular weight of the peptide. This verification step ensures that the sequence and structure of the synthesized peptide match the intended target, guaranteeing its identity .

Handling, Storage, and Reconstitution

Proper protocol is essential for maintaining peptide stability and ensuring experimental validity.

• 📦 Shipping & Packaging: We understand that peptide integrity is fragile. All orders are shipped in discreet, plain packaging with temperature-controlled insulation to protect the lyophilized powder during transit.
• ❄️ Storage Guidelines:
  • Lyophilized Powder: Store immediately upon receipt in a freezer at -18°C (0°F) or below for long-term storage. Keep the vial sealed, protected from light, and desiccated to prevent degradation. Lyophilized peptides are generally stable at room temperature for several weeks, but freezing is optimal for preserving stability over months or years .
  • Reconstituted Solution: Once reconstituted with bacteriostatic water, store the solution in a refrigerator at 2-8°C (36-46°F) . It is imperative to avoid repeated freeze-thaw cycles, as this will degrade the peptide. It is best practice to aliquot the solution into separate vials for single-use. After reconstitution, the peptides will remain stable for up to 30 days .
• 🧪 Instructions for Use (Research Only):
  1. Preparation: Allow the peptide vial and your chosen solvent (e.g., Bacteriostatic Water) to reach room temperature.
  2. Reconstitution: Using a sterile syringe, inject the solvent slowly down the inside wall of the vial. Swirl gently—do not shake vigorously, as this can damage the peptide structure .
  3. Dosage & Frequency: This product is for laboratory use only. Researchers should determine dosing based on their specific in-vitro or animal model protocols. There is no established human dosage. In research models, saturation dose for either peptide is often cited as approximately 100mcg (or 1mcg/kg) . Typical research protocols involve administration 2-3 times daily, spaced at least 3 hours apart, and timed around fasting states (1-2 hours after a meal and 20-30 minutes before eating) to avoid interference from glucose and fats .

Why Choose Buy Peptides Online USA?

When you need to buy Mod GRF 1-29 GHRP-2 blend for your next study, you need a partner who understands the stakes.

• 🏆 Authenticity Guarantee: We provide a full chain of traceability. Our products are sourced from GMP-compliant facilities, and our commitment to third-party verified analysis certificates ensures you are getting exactly what you need for reproducible science.
• 📞 Technical Consultation: Have questions about handling, solubility, or specifications? Our support team is well-versed in the technical aspects of our catalog and is ready to assist.
• 🚚 Fast & Discreet USA Shipping: We offer reliable shipping across the United States. For orders over $300, shipping is on us. We ensure your research materials arrive safely and on time.
• 🔒 Secure Checkout & Crypto Payments: We provide a seamless and secure ecommerce experience, including the option to pay with Bitcoin, Ethereum, and USDT for your convenience and privacy.

Frequently Asked Questions (FAQ)

Q: Is this blend for human or veterinary use?

A: No. This product is sold strictly for research and laboratory use only. It is not a drug, food, or cosmetic, and it is not intended for human consumption or veterinary use .

Q: What is the difference between Mod GRF (1-29) and CJC-1295 with DAC?

A: Mod GRF (1-29) is synonymous with CJC-1295 without DAC. The “No DAC” version lacks the Drug Affinity Complex. This means it has a short half-life and is designed for researchers studying natural, pulsatile GH release. The DAC version binds to albumin and creates a prolonged release, which may not accurately model physiological conditions .

Q: How is purity verified?

A: Purity is verified through High-Performance Liquid Chromatography (HPLC) , with our blend consistently achieving ≥99% purity. Identity is further confirmed via Mass Spectrometry (MS) . The Certificate of Analysis (COA) is available for your review .

Q: Do you ship to all states in the USA?

A: Yes, we offer fast and reliable shipping throughout the United States. All orders are packaged discreetly to ensure privacy and product integrity upon arrival.

Q: What payment methods do you accept?

A: We offer secure checkout with major credit cards and also accept cryptocurrencies like Bitcoin, Ethereum, and USDT for secure and private transactions.

Disclaimer: The products and information on this site are intended for research and educational purposes only. Buy Peptides Online USA does not promote or imply any use of these products for human consumption or as a drug. Always adhere to your institutional safety guidelines and local laws.